Double-Stranded DNA in Exosomes of Malignant Pleural Effusions as a Novel DNA Source for EGFR Mutation Detection in Lung Adenocarcinoma
Background: Exosomes are cell-derived vesicles and bear a specific set of nucleic acids including DNA (exoDNA).Thus, this study is to explore whether exoDNA in malignant pleural effusions (MPEs) could be a novel DNA source for mutation detection of epidermal growth factor receptor (EGFR).Methods: In this study, 52 53-264817 lung adenocarcinoma pati